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Es imprescindible evaluar la seguridad en poblaciones vulnerables adultos mayores, pacientes frgiles o con patologas neurodegenerativas y determinar la dosis-respuesta ptima para beneficios no metablicos

A promising area includes the development of dual and triple agonist drugs that target multiple receptors involved in appetite regulation and metabolism

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While it is as yet premature to integrate these agents into clinical practice, the researchers undertook a comprehensive overview of what we know so far about dual and triple agonists that target glucose-dependent insulinotropic polypeptide (GIP), another incretin

( g-h ) Same as ( c-d ), but cells were treated with olaparib (Olap) with or without supplementation with KG, l-carnitine or O-acetyl-l-carnitine